Powering the high-end market, my country's super-resolution optical microscope was successfully developed


   When it comes to the field of microorganisms, microscopy is an eternal topic. A microscope is an optical instrument composed of a lens or a combination of several lenses, and is a sign that mankind has entered the atomic age. With the development of new technologies such as materials, nanometers, optics, and semiconductors, the market demand for microscopes has been greatly promoted.   Microscopes can be divided into polarizing microscopes, optical microscopes, electron microscopes, and digital microscopes. In the early days, my country's microscope companies had low Ru0026D investment, and the design and technology of precision manufacturing and optical core components were far behind those of foreign countries. There were only a handful of companies capable of producing high-end microscopes, such as high-end products such as system microscopes, confocal scanning and super-resolution microscopes. It is firmly in the hands of imported brands.   Today, microscopes have been developed in my country for decades, and the annual output of microscopes exceeds 3 million. With the diversification and complexity of market demand and the continuous impact of new technologies, the task of developing high-end microscopes is particularly urgent.   Optical resolution microscope plays an important role in biology and medical research. For a long time, my country's technology in this field has been constrained by others, which has restricted innovative research in related fields to a certain extent. But researchers have never stopped pursuing technology. They always hope to get a microscope with higher resolution to better observe the microscopic world.   Ultra-high resolution microscope is one of the important research methods in the field of life sciences in recent years. In May 2018, the State Key Laboratory of Membrane Biology invented an ultra-sensitive Hessian structured light ultra-high resolution microscope. Realize ultra-fast long-term ultra-high-resolution imaging of living cells, which can distinguish vesicle fusion pores and mitochondrial cristae dynamics. It has extremely high time resolution, extremely low phototoxicity, and has significant advantages in ultra-high resolution imaging of living cells. After years of technological accumulation and major domestic scientific research progress, finally, on December 26, the national major scientific research equipment development project 'Super-resolution microscopy optics core components and system development' undertaken by Suzhou Medical Engineering Institute passed the acceptance, marking This means that my country has the ability to develop high-end super-resolution optical microscopes.   It is reported that the project has developed high-end optical microscopes such as laser scanning confocal microscopes, two-photon microscopes, stimulated emission loss (STED) super-resolution microscopes, and two-photon-STED microscopes. In addition, through this project, the Institute has built a high-end microscopic optical processing, assembly, inspection, and integrated engineering platform for microscope technology. It is expected to provide users with customized microscope equipment and provide a platform for the development of high-end optical microscopes in my country. System solutions.   Rooted in the low-end field, my country's high-end instruments have long relied on imports. This is an undeniable status quo in the development of the industry. In the future, with the penetration of domestic and foreign microscopes in teaching, life sciences, nanotechnology and semiconductor technology, as well as the upgrading and replacement of domestic microscope products, my country's microscope industry, especially in the high-end field, has a huge prospect. New microscope products that tend to be high-resolution, intelligent, digital, and integrated automation will be gradually developed.  As a major producer of microscopes in the world, my country's demand for high-end microscopes can be imagined. In the future, Ru0026D personnel will continue to work hard to improve the corresponding technology. The wider application of ultra-high-resolution microscopes has become the highlight of technological breakthroughs in the new year.

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